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Italian study shows COVID-19 infections and deaths plummeting after jabs

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COVID-19 infections in adults of all ages fell by 80% five weeks after a first dose of Pfizer (PFE.N), Moderna (MRNA.O) or AstraZeneca (AZN.L) vaccine, according to Italian research.

The first such study by a European Union country on the real-world impact of its immunization campaign was carried out by Italy's National Institute of Health (ISS) and the Ministry of Health on 13.7 million people vaccinated nationwide.

Scientists started studying data from the day Italy's vaccination campaign began, on Dec. 27 2020, until May 3 2021.

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The analysis showed that the risk of SARS-CoV-2 infection, hospitalisation, and death decreased progressively after the first two weeks following the initial vaccination.

"As of 35 days after the first dose, there is an 80% reduction in infections, 90% reduction in hospitalisations, and 95% reduction in deaths," the ISS said, adding that the same pattern was seen in both men and women regardless of age.

"This data confirms the effectiveness of the vaccination campaign and the need to achieve high coverage across the population quickly to end the emergency," ISS president Silvio Brusaferro said in the statement.

Among the nearly 14 million people included in the Italian study, 95% of those who had taken Pfizer and Moderna had completed the vaccine cycle, while none of those given AstraZeneca had received a second dose.

Up until now, Italy has been following the makers' recommendations, giving a second dose of Pfizer three weeks after the first, a second dose of Moderna after a four week gap and a second dose of AstraZeneca after a 12 week gap.

As of Saturday morning, some 8.3 million Italians, or 14% of the population, were completely vaccinated, while around 10 million people had received a first jab.

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EU Digital COVID Certificate: Commission adopts equivalence decisions for Vatican and San Marino certificates

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The Commission has adopted decisions ensuring that COVID-19 certificates issued by the Vatican City State and San Marino will be considered equivalent to the EU Digital COVID Certificate. This means that both countries will be connected to the EU's system and that COVID certificates issued by the Vatican and San Marino will be accepted in the EU under the same conditions as the EU Digital COVID Certificate. In practice, holders of these certificates will be able to use these certificates under the same conditions as holders of an EU Digital COVID Certificate. At the same time, the Vatican and San Marino have indicated that they would accept EU Digital COVID Certificates for travel to their countries.

Justice Commissioner Didier Reynders said: “I am pleased to see that more countries are implementing a system based on the EU Digital COVID Certificate. We are taking active steps to recognize certificates issued by other third countries. However, they must be interoperable with the EU framework and allow for the verification of their authenticity, validity and integrity.”

The Commission decisions on the equivalence of the Vatican and San Marino COVID certificates are available online. The Commission is also working on connecting other third countries. It checks if their certificates are interoperable with the EU Digital COVID Certificate, allowing for the verification of their authenticity, validity and integrity. The Commission can issue an equivalence decision establishing its equivalence with the EU Digital COVID Certificate. More information on the EU Digital COVID Certificate can be found on the dedicated website and Q&A.

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Republican report says coronavirus leaked from China lab - scientists still probing origins

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A computer image created by Nexu Science Communication together with Trinity College in Dublin, shows a model structurally representative of a betacoronavirus which is the type of virus linked to COVID-19, shared with Reuters on 18 February 2020. NEXU Science Communication/via REUTERS

A preponderance of evidence proves the virus that caused the COVID-19 pandemic leaked from a Chinese research facility, said a report by US Republicans released on Monday (2 August), a conclusion that US intelligence agencies have not reached, write Jonathan Landay and Mark Hosenball, Reuters.

The report also cited "ample evidence" that Wuhan Institute of Virology (WIV) scientists - aided by US experts and Chinese and US government funds - were working to modify coronaviruses to infect humans and such manipulation could be hidden.

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Representative Mike McCaul, the top Republican on the House Foreign Affairs Committee, released the report by the panel's Republican staff. It urged a bipartisan investigation into the origins of the COVID-19 coronavirus pandemic that has killed 4.4 million people worldwide. (Graphic on global cases and deaths).

China denies a genetically modified coronavirus leaked from the facility in Wuhan - where the first COVID-19 cases were detected in 2019 - a leading but unproven theory among some experts. Beijing also denies allegations of a cover-up.

Other experts suspect the pandemic was caused by an animal virus likely transmitted to humans at a seafood market near the WIV.

"We now believe it's time to completely dismiss the wet market as the source," said the report. "We also believe the preponderance of the evidence proves the virus did leak from the WIV and that it did so sometime before 12 September, 2019."

The report cited what it called new and under-reported information about safety protocols at the lab, including a July 2019 request for a $1.5 million overhaul of a hazardous waste treatment system for the facility, which was less than two years old.

In April, the top U.S. intelligence agency said it concurred with the scientific consensus that the virus was not man-made or genetically modified. Read more.

US President Joe Biden in May ordered US intelligence agencies to accelerate their hunt for the origins of the virus and report back in 90 days. Read more.

A source familiar with current intelligence assessments said the US intelligence community has not reached any conclusion whether the virus came from animals or the WIV.

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COVID-19 Delta variant gains prevalence in Italy - health institute

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People rest without wearing masks as Italy lifts mandatory masks outdoors thanks to a decline in the coronavirus disease (COVID-19) cases and hospitalizations, in Matera, Italy, 28 June. REUTERS/Yara Nardi

The highly contagious Delta variant of the coronavirus has gained dominance in Italy, the National Health Institute (ISS) said on Friday (30 July), releasing data showing it accounted for 94.8% of cases as of 20 July, writes Emilio Parodi, Reuters.

The variant, first identified in India in December 2020, is now dominant worldwide and has led to a spike in infection rates that has stoked concerns over the global economic recovery.

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In the previous survey based on data from 22 June, the Delta variant represented just 22.7% of cases. By contrast, the Alpha variant accounted for 3.2% of cases as of July 20 against a previous prevalence of 57.8%.

"It is essential to continue the systematic tracking of cases and to complete the vaccination cycle as quickly as possible", ISS President Silvio Brusaferro said in a statement.

The ISS said its survey did not include all variant cases but only those detected on the day it was carried out. It added that the Gamma variant, first identified in Brazil, fell to 1.4% of cases from 11.8% in the past survey.

The institute also pointed out an "extremely small increase" in cases of the Beta variant, first identified in South Africa, which it says is characterised by partial immune evasion.

Italy has registered 128,029 deaths linked to COVID-19 since its outbreak emerged in February last year, the second-highest toll in Europe after Britain and the eighth-highest in the world. It has reported 4.34 million cases to date.

Almost 59% of Italians over 12 years were fully vaccinated as of Friday, while about 10% are awaiting their second dose.

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